Methodological Research:
Design of group sequential clinical trials
Design of trials to evaluate new screening tests
Designing clinical trials with multiple endpoints
Use of mediation models for biomarker evaluation
Applications:
Colorado lung SPORE: Evaluation of biomarkers for lung cancer. Phase II chemoprevention trial in
subjects at high risk for lung cancer.
Colorado General Clinical Research Center: Statistical consulation for design and analysis
of GCRC studies. Statistical review for the GCRC scientific advisory committee. Safety monitoring of
GCRC studies.
San Luis Valley Healthy Family Project: Randomized-controlled trial of a family intervention for
reduction of diabetes risk.
For futher details:
Curriculum Vita