David Pollock, Ph.D.

    Associate Professor

    Biochemistry and Molecular Genetics

    Computational Bioscience Program

    University of Colorado at Denver

    and Health Sciences Center

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Short Biosketch:

Received his Ph.D. in Biological Sciences from Stanford University in 1995, and then spent 5 years at the National Institute for Medical Research in London, UC Berkeley, and Los Alamos National Laboratories on a Hitchings-Elion Fellowship from the Wellcome Trust, and a Director's Fellowship from LANL. Following this he sent 6 years at Louisiana State University. Dr. Pollock's research interests are in evolutionary genomics and molecular evolution, particularly the interaction between protein sequence, structure, and function, and molecular coevolution within and between proteins. Computational approaches include development of phylogeny-based context-dependent likelihood and Bayesian approaches to analysis of sequence evolution, "conditional pathways", MCMC, mixture models, hidden Markov models, Markov random fields, mathematical analysis of population genetics, simulation, and molecular dynamic and lattice-based evaluation of protein stability and function in a thermodynamic context. Current study systems include vertebrate mitochondrial genomes, cytochrome oxidase, photolyase, HIV protease, and lysozyme, and I am a founding member of consortia to analyze the upcoming Monodelphis domestica and Anolis carolinensis complete genomes.

Updated 5/24/2006